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RORC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

RORC Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731080
  • Target See all RORC Proteins
    RORC (RAR-Related Orphan Receptor C (RORC))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 5
    • 2
    • 2
    Human
    Source
    • 5
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This RORC protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ROR-gamma / RORC (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RORC Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RORC (RAR-Related Orphan Receptor C (RORC))
    Alternative Name
    Ror-Gamma,rorc (RORC Products)
    Synonyms
    NR1F3 Protein, RORG Protein, RZR-GAMMA Protein, RZRG Protein, TOR Protein, Nr1f3 Protein, RORgamma Protein, Thor Protein, RAR related orphan receptor C Protein, RAR-related orphan receptor C Protein, RAR-related orphan receptor gamma Protein, RORC Protein, Rorc Protein
    Background
    The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    58 kDa
    NCBI Accession
    NP_005051
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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