RORC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all RORC Proteins
- RORC (RAR-Related Orphan Receptor C (RORC))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RORC protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ROR-gamma / RORC (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RORC Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RORC (RAR-Related Orphan Receptor C (RORC))
- Alternative Name
- Ror-Gamma,rorc (RORC Products)
- Synonyms
- NR1F3 Protein, RORG Protein, RZR-GAMMA Protein, RZRG Protein, TOR Protein, Nr1f3 Protein, RORgamma Protein, Thor Protein, RAR related orphan receptor C Protein, RAR-related orphan receptor C Protein, RAR-related orphan receptor gamma Protein, RORC Protein, Rorc Protein
- Background
- The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 58 kDa
- NCBI Accession
- NP_005051
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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