RRM2B Protein (Myc-DYKDDDDK Tag)
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- Target See all RRM2B Proteins
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RRM2B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RRM2B / P53R2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RRM2B Protein
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Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 3-84) protein (GST tag)
RRM2B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 1-351) protein (Strep Tag)Crystallography grade RRM2B Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 1-351) protein (Strep Tag)Crystallography grade RRM2B Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- Alternative Name
- Rrm2b,p53r2 (RRM2B Products)
- Synonyms
- p53r2 Protein, RRM2B Protein, MTDPS8A Protein, MTDPS8B Protein, P53R2 Protein, p53R2 Protein, ribonucleotide reductase M2 B (TP53 inducible) S homeolog Protein, ribonucleotide reductase regulatory TP53 inducible subunit M2B Protein, ribonucleotide reductase M2 B (TP53 inducible) Protein, rrm2b.S Protein, RRM2B Protein, rrm2b Protein, Rrm2b Protein
- Background
- This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
- Molecular Weight
- 40.6 kDa
- NCBI Accession
- NP_056528
- Pathways
- p53 Signaling, Negative Regulation of intrinsic apoptotic Signaling
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