RSPO2 Protein
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- Target See all RSPO2 Proteins
- RSPO2 (R-Spondin 2 (RSPO2))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- CHO Cells
- Application
- Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human RSPO2 protein expressed in CHO cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- R-Spondin-2 enhances BMP-2 mediated differentiation of MC3T3-E1 cells.
- Top Product
- Discover our top product RSPO2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RSPO2 (R-Spondin 2 (RSPO2))
- Alternative Name
- Rspo2 (RSPO2 Products)
- Synonyms
- RGD1562331 Protein, CRISTIN2 Protein, 2610028F08Rik Protein, AA673245 Protein, D430027K22 Protein, ftls Protein, R-spondin 2 Protein, R-spondin 2 L homeolog Protein, Rspo2 Protein, rspo2.L Protein, rspo2 Protein, RSPO2 Protein
- Background
- This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 24.4 kDa
- NCBI Accession
- NP_848660
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