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RSPO2 Protein

RSPO2 Origin: Human Host: CHO Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Catalog No. ABIN2731227
  • Target See all RSPO2 Proteins
    RSPO2 (R-Spondin 2 (RSPO2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    CHO Cells
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human RSPO2 protein expressed in CHO cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    R-Spondin-2 enhances BMP-2 mediated differentiation of MC3T3-E1 cells.
    Top Product
    Discover our top product RSPO2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handling Advice
    Resuspend the protein in the desired concentration in proper buffer
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RSPO2 (R-Spondin 2 (RSPO2))
    Alternative Name
    Rspo2 (RSPO2 Products)
    Synonyms
    RGD1562331 Protein, CRISTIN2 Protein, 2610028F08Rik Protein, AA673245 Protein, D430027K22 Protein, ftls Protein, R-spondin 2 Protein, R-spondin 2 L homeolog Protein, Rspo2 Protein, rspo2.L Protein, rspo2 Protein, RSPO2 Protein
    Background
    This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    24.4 kDa
    NCBI Accession
    NP_848660
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