SEC31A Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all SEC31A Proteins
- SEC31A (SEC31 Homolog A (SEC31A))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SEC31A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SEC31A (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SEC31A Protein
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SEC31 Homolog A (SEC31A) (AA 1-509) protein (GST tag)
SEC31A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
SEC31 Homolog A (SEC31A) (AA 1-1220) protein (Strep Tag)Crystallography grade SEC31A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
SEC31 Homolog A (SEC31A) (AA 1-1230) protein (Strep Tag)Crystallography grade SEC31A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SEC31A (SEC31 Homolog A (SEC31A))
- Alternative Name
- Sec31a (SEC31A Products)
- Synonyms
- ABP125 Protein, ABP130 Protein, HSPC334 Protein, SEC31L1 Protein, Sec31l1 Protein, VAP1 Protein, 1810024J13Rik Protein, AU042160 Protein, HSPC275 Protein, cb354 Protein, sec31p Protein, zgc:63547 Protein, SEC31 homolog A, COPII coat complex component Protein, Sec31 homolog A (S. cerevisiae) Protein, SEC31A Protein, Sec31a Protein, sec31a Protein
- Background
- The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 131.4 kDa
- NCBI Accession
- NP_001070676
- Pathways
- ER-Nucleus Signaling
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