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SH2B2 Protein (Myc-DYKDDDDK Tag)

SH2B2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731946
  • Target See all SH2B2 Proteins
    SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SH2B2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SH2B2 / APS protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SH2B2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
    Alternative Name
    Sh2b2,aps (SH2B2 Products)
    Synonyms
    APS Protein, Aps Protein, SH2B adaptor protein 2 Protein, SH2B2 Protein, Sh2b2 Protein
    Background
    The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt&aposs lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
    Molecular Weight
    72.1 kDa
    NCBI Accession
    NP_066189
    Pathways
    Carbohydrate Homeostasis, Brown Fat Cell Differentiation
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