SHOX2 Protein (His tag)

Catalog No. ABIN2732010

Product Details

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SHOX2 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SHOX2 / SHOT (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Alternative Name: Shox2,shot (SHOX2 Products)

Synonyms: SHOX2 Protein, og12 Protein, shot Protein, og12x Protein, ogi2x Protein, OG12 Protein, OG12X Protein, SHOT Protein, 6330543G17Rik Protein, Og12x Protein, Prx3 Protein, zgc:65884 Protein, zgc:77344 Protein, short stature homeobox 2 Protein, SHOX2 Protein, shox2 Protein, Shox2 Protein

Background: This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight: 34.8 kDa

NCBI Accession: NP_006875

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development