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SNX15 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

SNX15 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732393
  • Target See all SNX15 Proteins
    SNX15 (Sorting Nexin 15 (SNX15))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant A
    Origin
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This SNX15 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Sorting nexin-15 (SNX15) (transcript variant A) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SNX15 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SNX15 (Sorting Nexin 15 (SNX15))
    Alternative Name
    Sorting Nexin-15 (Snx15) (SNX15 Products)
    Synonyms
    SNX15 Protein, hsaf001435 Protein, snx15 Protein, MGC154249 Protein, HSAF001435 Protein, 1500032B08Rik Protein, E130013C21Rik Protein, sorting nexin 15 Protein, sorting nexin 15 S homeolog Protein, SNX15 Protein, snx15.S Protein, snx15 Protein, Snx15 Protein
    Background
    This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
    Molecular Weight
    38.1 kDa
    NCBI Accession
    NP_037438
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