SPG20 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all SPG20 Proteins
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPG20 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Spartin / SPG20 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPG20 Protein
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Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (AA 1-666) protein (His tag)
Crystallography grade SPG20 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (AA 1-671) protein (His tag)Crystallography grade SPG20 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SPG20 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)SPG20 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)SPG20 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
- Alternative Name
- Spartin,spg20 (SPG20 Products)
- Synonyms
- SPARTIN Protein, TAHCCP1 Protein, AI840044 Protein, C79168 Protein, mKIAA0610 Protein, spartin Protein, Spg20 Protein, spg20a Protein, zgc:172059 Protein, spg20b Protein, zgc:153766 Protein, spartin Protein, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) Protein, spartin a Protein, spartin b Protein, SPART Protein, Spg20 Protein, Spart Protein, sparta Protein, spartb Protein
- Background
- This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
- Molecular Weight
- 72.7 kDa
- NCBI Accession
- NP_001135767
- Pathways
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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