SPATA18 Protein (Myc-DYKDDDDK Tag)
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- Target See all SPATA18 Proteins
- SPATA18 (Spermatogenesis Associated 18 (SPATA18))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPATA18 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SPATA18 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPATA18 Protein
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Spermatogenesis Associated 18 (SPATA18) (AA 1-538) protein (Strep Tag)
Crystallography grade SPATA18 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Spermatogenesis Associated 18 (SPATA18) (AA 1-537) protein (Strep Tag)Crystallography grade SPATA18 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPATA18 (Spermatogenesis Associated 18 (SPATA18))
- Alternative Name
- Spata18 (SPATA18 Products)
- Synonyms
- Mieap Protein, SPETEX1 Protein, 1700067I02Rik Protein, MIEAP Protein, spetex-1 Protein, mieap Protein, spetex1 Protein, im:7140046 Protein, zgc:110352 Protein, spermatogenesis associated 18 Protein, spermatogenesis associated 18 L homeolog Protein, SPATA18 Protein, Spata18 Protein, spata18.L Protein, spata18 Protein
- Background
- This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 60.9 kDa
- NCBI Accession
- NP_660306
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