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SPDEF/PSE Protein (Myc-DYKDDDDK Tag)

SPDEF Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732544
  • Target See all SPDEF/PSE (SPDEF) Proteins
    SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This SPDEF/PSE protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SPDEF protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SPDEF Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
    Alternative Name
    Spdef (SPDEF Products)
    Synonyms
    PDEF Protein, RP11-375E1__A.3 Protein, bA375E1.3 Protein, pdef Protein, Pse Protein, SAM pointed domain containing ETS transcription factor Protein, SAM pointed domain containing ets transcription factor Protein, SPDEF Protein, Spdef Protein
    Background
    The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    37.3 kDa
    NCBI Accession
    NP_036523
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