SPDEF/PSE Protein (Myc-DYKDDDDK Tag)
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- Target See all SPDEF/PSE (SPDEF) Proteins
- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPDEF/PSE protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SPDEF protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPDEF Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
- Alternative Name
- Spdef (SPDEF Products)
- Synonyms
- PDEF Protein, RP11-375E1__A.3 Protein, bA375E1.3 Protein, pdef Protein, Pse Protein, SAM pointed domain containing ETS transcription factor Protein, SAM pointed domain containing ets transcription factor Protein, SPDEF Protein, Spdef Protein
- Background
- The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 37.3 kDa
- NCBI Accession
- NP_036523
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