SPTLC1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732627

Product Details

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SPTLC1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SPTLC1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Alternative Name: Sptlc1 (SPTLC1 Products)

Synonyms: ATSPT1 Protein, SERINE PALMITOYLTRANSFERASE 1 Protein, serine palmitoyltransferase 1 Protein, Afu6g00300 Protein, HSAN1 Protein, HSN1 Protein, LBC1 Protein, LCB1 Protein, SPT1 Protein, SPTI Protein, wu:fc75h04 Protein, wu:fp41c08 Protein, zgc:112247 Protein, AW552086 Protein, C77762 Protein, E030036H05 Protein, Lcb1 Protein, RGD1306617 Protein, Spt1 Protein, serine palmitoyltransferase 1 Protein, Serine palmitoyltransferase 1 Protein, serine palmitoyltransferase long chain base subunit 1 Protein, serine palmitoyltransferase, long chain base subunit 1 Protein, serine palmitoyltransferase, long chain base subunit 1 L homeolog Protein, SPT1 Protein, AFUA_6G00300 Protein, PAS_FragB_0040 Protein, SPTLC1 Protein, sptlc1 Protein, sptlc1.L Protein, Sptlc1 Protein

Background: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5&apos-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.

Molecular Weight: 52.6 kDa

NCBI Accession: NP_006406