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SSB Protein (Myc-DYKDDDDK Tag)

SSB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732688
  • Target See all SSB Proteins
    SSB (Sjogren Syndrome Antigen B (SSB))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SSB protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SS-B / La protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SSB Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SSB (Sjogren Syndrome Antigen B (SSB))
    Alternative Name
    Ss-B,la (SSB Products)
    Synonyms
    LARP3 Protein, La Protein, lab1 Protein, larp3 Protein, ssb Protein, Mt-SSB Protein, MtSSB Protein, Ssbp1 Protein, SS-B Protein, laa-a Protein, ssb-a Protein, ssb-b Protein, wu:fb17f11 Protein, zgc:55588 Protein, Sjogren syndrome antigen B Protein, Sjogren syndrome antigen B L homeolog Protein, single stranded DNA binding protein 1 Protein, Sjogren syndrome antigen B S homeolog Protein, Sjogren syndrome antigen B (autoantigen La) Protein, SSB Protein, ssb.L Protein, SSBP1 Protein, Ssb Protein, ssb.S Protein, ssb Protein
    Background
    The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5&apos and 3&apos ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
    Molecular Weight
    46.7 kDa
    NCBI Accession
    NP_003133
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