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SSX2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SSX2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732726
  • Target See all SSX2 Proteins
    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SSX2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SSX2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SSX2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))
    Alternative Name
    Ssx2 (SSX2 Products)
    Synonyms
    CT5.2 Protein, CT5.2A Protein, HD21 Protein, HOM-MEL-40 Protein, SSX Protein, SSX2 Protein, SSX3 Protein, SSX family member 2 Protein, protein SSX2 Protein, synovial sarcoma, X breakpoint 2 Protein, SSX2 Protein, LOC741661 Protein, Ssx2 Protein
    Background
    The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X18)(p11.2q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.
    Molecular Weight
    25 kDa
    NCBI Accession
    NP_003138
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