STAM Protein (Myc-DYKDDDDK Tag)
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- Target See all STAM Proteins
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This STAM protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human STAM1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product STAM Protein
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Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 1-403) protein (GST tag)
STAM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 2-540) protein (His tag)Crystallography grade STAM Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 2-548) protein (His tag)Crystallography grade STAM Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
- Alternative Name
- Stam1 (STAM Products)
- Synonyms
- STAM-1 Protein, STAM1 Protein, wu:fv75b10 Protein, zgc:55725 Protein, RGD1564499 Protein, signal transducing adaptor molecule Protein, signal transducing adapter molecule 1 Protein, Signal transducing adapter molecule 1 Protein, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 Protein, STAM Protein, CpipJ_CPIJ003516 Protein, Tsp_03939 Protein, stam-1 Protein, Stam Protein, stam Protein
- Background
- Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 59 kDa
- NCBI Accession
- NP_003464
- Pathways
- EGFR Signaling Pathway, EGFR Downregulation
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