STAT2 Protein (Myc-DYKDDDDK Tag)
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- Target See all STAT2 Proteins
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This STAT2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human STAT2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product STAT2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- Alternative Name
- Stat2 (STAT2 Products)
- Synonyms
- wu:fj84d07 Protein, p113 Protein, stat2 Protein, 1600010G07Rik Protein, AW496480 Protein, ISGF-3 Protein, P113 Protein, STAT113 Protein, signal transducer and activator of transcription 2 Protein, AGAP000099-PA Protein, stat2 Protein, STAT2 Protein, Stat2 Protein
- Background
- The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 97.7 kDa
- NCBI Accession
- NP_005410
- Pathways
- JAK-STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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