STK38 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732876

Product Details

Target: STK38 (serine/threonine Kinase 38 (STK38))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This STK38 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human STK38 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Wen, Ma, Cheng, Jiang, Xu, Zhang, Zhang, Guo, Yu, Xu, Qian, Cao, An: "Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages." in: Nature communications, Vol. 6, pp. 7167, (2015) (PubMed).

Target Details

Target: STK38 (serine/threonine Kinase 38 (STK38))

Alternative Name: Stk38 (STK38 Products)

Synonyms: NDR Protein, NDR1 Protein, 5830476G13Rik Protein, 9530097A09Rik Protein, AA617404 Protein, Ndr1 Protein, trc Protein, si:ch1073-272h17.2 Protein, wu:fj80h03 Protein, zgc:55572 Protein, serine/threonine kinase 38 Protein, serine/threonine kinase 38 S homeolog Protein, serine/threonine kinase 38b Protein, serine/threonine kinase 38a Protein, STK38 Protein, Stk38 Protein, stk38.S Protein, stk38b Protein, stk38a Protein

Background: This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.

Molecular Weight: 54 kDa

NCBI Accession: NP_009202