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SUCLA2 Protein (Myc-DYKDDDDK Tag)

SUCLA2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732921
  • Target See all SUCLA2 Proteins
    SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SUCLA2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SUCLA2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SUCLA2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))
    Alternative Name
    Sucla2 (SUCLA2 Products)
    Synonyms
    4930547K18Rik Protein, A-BETA Protein, MTDPS5 Protein, SCS-betaA Protein, SCS Protein, succinate-Coenzyme A ligase, ADP-forming, beta subunit Protein, succinate-CoA ligase ADP-forming beta subunit Protein, Sucla2 Protein, SUCLA2 Protein
    Background
    Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
    Molecular Weight
    44.5 kDa
    NCBI Accession
    NP_003841
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