TARBP2 Protein (His tag)

Catalog No. ABIN2733237

Product Details

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TARBP2 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TARBP2 (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Alternative Name: Tarbp2 (TARBP2 Products)

Synonyms: trbp Protein, trbp1 Protein, trbp2 Protein, MGC97783 Protein, TARBP2 Protein, LOQS Protein, TRBP Protein, TRBP1 Protein, TRBP2 Protein, fj51e12 Protein, wu:fj51e12 Protein, zgc:63778 Protein, Prbp Protein, TAR (HIV-1) RNA binding protein 2 Protein, TARBP2, RISC loading complex RNA binding subunit Protein, TAR (HIV-1) RNA binding protein 2 L homeolog Protein, TAR (HIV) RNA binding protein 2 Protein, tarbp2 Protein, TARBP2 Protein, tarbp2.L Protein, Tarbp2 Protein

Background: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.

Molecular Weight: 36.7 kDa

NCBI Accession: NP_599151

Pathways: Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization