Thimet Oligopeptidase 1 Protein (THOP1) (Myc-DYKDDDDK Tag)
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- Target See all Thimet Oligopeptidase 1 (THOP1) Proteins
- Thimet Oligopeptidase 1 (THOP1)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Thimet Oligopeptidase 1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Thimet oligopeptidase (THOP1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product THOP1 Protein
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Thimet Oligopeptidase 1 (THOP1) (AA 1-689) protein (GST tag)
THOP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Thimet Oligopeptidase 1 (THOP1) (AA 255-354) protein (GST tag)THOP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Thimet Oligopeptidase 1 (THOP1) (Active) protein (His tag)THOP1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE Active
Thimet Oligopeptidase 1 (THOP1) (AA 1-689) protein (Strep Tag)Crystallography grade THOP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Thimet Oligopeptidase 1 (THOP1) (AA 1-687) protein (Strep Tag)Crystallography grade THOP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Thimet Oligopeptidase 1 (THOP1)
- Alternative Name
- Thimet Oligopeptidase (Thop1) (THOP1 Products)
- Synonyms
- EP24.15 Protein, MEPD_HUMAN Protein, MP78 Protein, TOP Protein, AI131655 Protein, AI327041 Protein, THOP1 Protein, thop1 Protein, MGC147297 Protein, LOC397806 Protein, mepd Protein, thimet oligopeptidase 1 Protein, thimet oligopeptidase 1 L homeolog Protein, thimet oligopeptidase Protein, peptidase Protein, Thimet oligopeptidase Protein, THOP1 Protein, Thop1 Protein, thop1 Protein, thop1.L Protein, Tc00.1047053506411.10 Protein, Tc00.1047053511237.10 Protein, Noca_4613 Protein, ANI_1_1400064 Protein, MBOO_RS10705 Protein, AOR_1_880174 Protein, AnaeK_0425 Protein, MPAL_RS03920 Protein, Hoch_5061 Protein, mepd Protein
- Background
- The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.
- Molecular Weight
- 78.7 kDa
- NCBI Accession
- NP_003240
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