TMSB4X Protein

Catalog No. ABIN2733660

Product Details

Target: TMSB4X (Thymosin beta-4 (TMSB4X))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

Specificity: Optimal preservation of protein structure, post-translational modifications and functions.

Characteristics:

• Recombinant human Thymosin beta-4 protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: Pretreatment of primary lung fibroblasts with recombinant Thymosin-beta4, using a concentration of 0.5 - 10 ug/mL, produces a protective effect against hydrogen peroxide induced cell death.

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Handling Advice: Resuspend the protein in the desired concentration in proper buffer

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TMSB4X (Thymosin beta-4 (TMSB4X))

Alternative Name: Thymosin beta-4 (TMSB4X Products)

Synonyms: FX Protein, PTMB4 Protein, TB4X Protein, TMSB4 Protein, Ptmb4 Protein, Tb4 Protein, tmsb4 Protein, TMSB4X Protein, thymosin beta 4, X-linked Protein, thymosin, beta 4, X chromosome Protein, thymosin beta 4, X-linked L homeolog Protein, thymosin, beta 4-like Protein, thymosin beta 4 pseudogene Protein, TMSB4X Protein, Tmsb4x Protein, tmsb4x.L Protein, TMSB4 Protein, LOC100339394 Protein, LOC100860922 Protein

Background: This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y.

Molecular Weight: 5.2 kDa

NCBI Accession: NP_066932

Pathways: Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Smooth Muscle Cell Migration