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TSH receptor Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

TSHR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733690
  • Target See all TSH receptor (TSHR) Proteins
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 6
    • 2
    • 1
    Human
    Source
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TSH receptor protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Thyrotropin receptor / TSHR (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TSHR Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Alternative Name
    Thyrotropin Receptor,tshr (TSHR Products)
    Synonyms
    CHNG1 Protein, LGR3 Protein, hTSHR-I Protein, AI481368 Protein, hypothroid Protein, hyt Protein, pet Protein, TSHRA Protein, TSH-R Protein, thyroid stimulating hormone receptor Protein, tshr Protein, TSHR Protein, Tshr Protein
    Background
    The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    28.5 kDa
    NCBI Accession
    NP_001136098
    Pathways
    Thyroid Hormone Synthesis
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