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TICAM2 Protein (Myc-DYKDDDDK Tag)

TICAM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733703
  • Target See all TICAM2 Proteins
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 1
    • 1
    Human
    Source
    • 6
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TICAM2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TICAM2 / TRAM protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TICAM2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Alternative Name
    Ticam2,tram (TICAM2 Products)
    Synonyms
    MyD88-4 Protein, TICAM-2 Protein, TIRAP3 Protein, TIRP Protein, TRAM Protein, B430113A10 Protein, Tirp Protein, Trif Protein, toll like receptor adaptor molecule 2 Protein, toll-like receptor adaptor molecule 2 Protein, TICAM2 Protein, Ticam2 Protein
    Background
    Isoform 2: Proposed to inhibit LPS-TLR4 signaling at the late endosome by interaction with isoform 1 thereby disrupting the association of isoform 1 with TICAM1. May be involved in TLR4 degradation in late endosomes. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    26.7 kDa
    NCBI Accession
    NP_067681
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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