Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TRAF1 Protein (Myc-DYKDDDDK Tag)

TRAF1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734111
  • Target See all TRAF1 Proteins
    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    Human
    Source
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TRAF1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TRAF1 / EBI6 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TRAF1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
    Alternative Name
    Traf1,ebi6 (TRAF1 Products)
    Synonyms
    CG3048 Protein, DTRAF Protein, DTRAF1 Protein, Dmel\\CG3048 Protein, TRAF Protein, TRAF1 Protein, Traf1 Protein, dTRAF Protein, dTRAF1 Protein, dTraf1 Protein, dtraf1 Protein, traf1 Protein, traf4 Protein, DKFZp469G032 Protein, EBI6 Protein, MGC:10353 Protein, 4732496E14Rik Protein, TNF receptor associated factor 1 Protein, TNF-receptor-associated factor 4 Protein, TNF receptor-associated factor 1 Protein, TRAF1 Protein, Traf4 Protein, Traf1 Protein, traf1 Protein
    Background
    The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.
    Molecular Weight
    46 kDa
    NCBI Accession
    NP_005649
    Pathways
    NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
You are here:
Support