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TRAF3 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

TRAF3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734113
  • Target See all TRAF3 Proteins
    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This TRAF3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TRAF3 / CRAF1 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TRAF3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
    Alternative Name
    Traf3,craf1 (TRAF3 Products)
    Synonyms
    CAP-1 Protein, CAP1 Protein, CD40bp Protein, CRAF1 Protein, IIAE5 Protein, LAP1 Protein, AI528849 Protein, T-BAM Protein, amn Protein, TNF receptor associated factor 3 Protein, TNF receptor-associated factor 3 Protein, Tnf receptor-associated factor 3 Protein, TRAF3 Protein, Traf3 Protein
    Background
    The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
    Molecular Weight
    64.3 kDa
    NCBI Accession
    NP_003291
    Pathways
    NF-kappaB Signaling, Apoptosis, TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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