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TGM1 Protein (Myc-DYKDDDDK Tag)

TGM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734144
  • Target See all TGM1 Proteins
    TGM1 (Transglutaminase 1, Keratinocyte (TGM1))
    Protein Type
    Recombinant
    Origin
    • 6
    • 5
    • 2
    • 2
    • 2
    Human
    Source
    • 11
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TGM1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Transglutaminase-1 (TGM1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TGM1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TGM1 (Transglutaminase 1, Keratinocyte (TGM1))
    Alternative Name
    Transglutaminase-1 (Tgm1) (TGM1 Products)
    Synonyms
    TGM1 Protein, ARCI1 Protein, ICR2 Protein, KTG Protein, LI Protein, LI1 Protein, TGASE Protein, TGK Protein, 2310004J08Rik Protein, Tgase1 Protein, transglutaminase 1 Protein, transglutaminase 1, K polypeptide Protein, Tgm1 Protein, TGM1 Protein
    Background
    The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).
    Molecular Weight
    89.6 kDa
    NCBI Accession
    NP_000350
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