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TRIB2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

TRIB2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734213
  • Target See all TRIB2 Proteins
    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TRIB2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TRIB2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TRIB2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
    Alternative Name
    Trib2 (TRIB2 Products)
    Synonyms
    TRIB2 Protein, Trb2 Protein, Xtrbl Protein, gs3955 Protein, c5fw Protein, trb2 Protein, xtrb2 Protein, TRB2 Protein, C5FW Protein, GS3955 Protein, TRB-2 Protein, AW319517 Protein, RGD1564451 Protein, tribbles pseudokinase 2 Protein, tribbles pseudokinase 2 S homeolog Protein, TRIB2 Protein, trib2 Protein, trib2.S Protein, Trib2 Protein
    Background
    This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
    Molecular Weight
    38.6 kDa
    NCBI Accession
    NP_067675
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