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NTRK3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

NTRK3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734342
  • Target See all NTRK3 Proteins
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 17
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This NTRK3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TrkC (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NTRK3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    Alternative Name
    Trkc (NTRK3 Products)
    Synonyms
    TRKC Protein, gp145(trkC) Protein, trkC Protein, AW125844 Protein, Ntrk3_tv3 Protein, TrkC Protein, neurotrophic receptor tyrosine kinase 3 Protein, neurotrophic tyrosine kinase, receptor, type 3 Protein, NTRK3 Protein, Ntrk3 Protein
    Background
    This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    90.9 kDa
    NCBI Accession
    NP_001012338
    Pathways
    RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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