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SNRPA1 Protein (Myc-DYKDDDDK Tag)

SNRPA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Catalog No. ABIN2734735
  • Target See all SNRPA1 (SNRPA) Proteins
    SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SNRPA1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human U1 snRNP protein A protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Biological Activity Comment
    : OriGene human recombinant small nuclear ribonucleoprotein polypeptide A (SNRPA) was compared side-by-side with baculovirus based insect cell (BEVS) derived SNRPA in a phycoerythrin detecting Luminex assay. The human cell produced SNRPA is comparative or better in sensitivity than the insect cell produced SNRPA to detect autoantibodies in human serum samples.
    Top Product
    Discover our top product SNRPA Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))
    Alternative Name
    u1 Snrnp Protein A (SNRPA Products)
    Synonyms
    Mud1 Protein, U1-A Protein, U1A Protein, im:7142962 Protein, zgc:101832 Protein, C430021M15Rik Protein, Rnu1a-1 Protein, Rnu1a1 Protein, mud1 Protein, snf Protein, fc19d01 Protein, wu:fc19d01 Protein, zgc:77810 Protein, T30B22.12 Protein, U1SNRNP-SPECIFIC PROTEIN Protein, spliceosomal protein U1A Protein, small nuclear ribonucleoprotein polypeptide A Protein, small nuclear ribonucleoprotein polypeptide A' Protein, small nuclear ribonucleoprotein polypeptide A S homeolog Protein, spliceosomal protein U1A Protein, SNRPA Protein, snrpa1 Protein, Snrpa Protein, snrpa.S Protein, snrpa Protein, U1A Protein
    Background
    The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5&apos splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
    Molecular Weight
    31.1 kDa
    NCBI Accession
    NP_004587
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