UGT2B15 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734994

Product Details

Target: UGT2B15 (UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This UGT2B15 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human UGT2B15 / UGT2B8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Divakaran, Hines, McCarver: "Human hepatic UGT2B15 developmental expression." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 141, Issue 1, pp. 292-9, (2014) (PubMed).

Target Details

Target: UGT2B15 (UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15))

Alternative Name: Ugt2b15,ugt2b8 (UGT2B15 Products)

Synonyms: UGT2B28 Protein, HLUG4 Protein, UDPGT 2B8 Protein, UDPGT2B15 Protein, UDPGTH3 Protein, UGT2B8 Protein, UDP-glucuronosyltransferase 2B15 Protein, UDP glucuronosyltransferase family 2 member B15 Protein, LOC461289 Protein, LOC100591991 Protein, UGT2B15 Protein

Background: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens. [UniProtKB/Swiss-Prot Function]

Molecular Weight: 60.9 kDa

NCBI Accession: NP_001067

Pathways: Steroid Hormone Biosynthesis