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VAV3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

VAV3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2735200
  • Target See all VAV3 Proteins
    VAV3 (Vav 3 Oncogene (VAV3))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This VAV3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human VAV3 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product VAV3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    VAV3 (Vav 3 Oncogene (VAV3))
    Alternative Name
    Vav3 (VAV3 Products)
    Synonyms
    RGD1565941 Protein, A530094I06Rik Protein, AA986410 Protein, Idd18.1 Protein, vav guanine nucleotide exchange factor 3 Protein, vav 3 guanine nucleotide exchange factor Protein, vav 3 oncogene Protein, VAV3 Protein, Vav3 Protein
    Background
    This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Molecular Weight
    32.4 kDa
    NCBI Accession
    NP_001073343
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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