ZNF346 Protein (Myc-DYKDDDDK Tag)
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- Target See all ZNF346 Proteins
- ZNF346 (Zinc Finger Protein 346 (ZNF346))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ZNF346 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ZNF346 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ZNF346 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ZNF346 (Zinc Finger Protein 346 (ZNF346))
- Alternative Name
- Znf346 (ZNF346 Products)
- Synonyms
- ZNF346 Protein, jaz Protein, zfp346 Protein, JAZ Protein, Zfp346 Protein, Jaz Protein, Znf346 Protein, im:7136406 Protein, wu:fc21c04 Protein, zgc:158750 Protein, DsRBP-ZFa Protein, ZFa Protein, zinc finger protein 346 Protein, zinc finger protein 346 S homeolog Protein, Zfp346 Protein, ZNF346 Protein, znf346 Protein, znf346.S Protein
- Background
- The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.
- Molecular Weight
- 32.8 kDa
- NCBI Accession
- NP_036411
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