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CBP Protein (His tag)

CREBBP Origin: Mouse Host: Insect cells (Sf21) Recombinant >95 % (SDS-PAGE) SDS Active
Catalog No. ABIN2745629
  • Target See all CBP (CREBBP) Proteins
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 6
    • 2
    • 2
    Mouse
    Source
    • 8
    • 1
    • 1
    • 1
    Insect cells (Sf21)
    Purification tag / Conjugate
    This CBP protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Cross-Reactivity
    Mouse (Murine)
    Characteristics
    Mouse full-length CREB-binding protein fused at the C-terminus to a His-tag.
    Purity
    >95 % (SDS-PAGE)
    Top Product
    Discover our top product CREBBP Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    ~50-100ng are required for standard HAT assay.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2 % NP-40, 50-100 mM imidazole and 10 % glycerol.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Short Term Storage: -20°C
    Long Term Storage: -80°C
    Stable for at least 6 months after receipt when stored at -80°C.
    Expiry Date
    6 months
  • Target
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Alternative Name
    CREB-Binding Protein (CREBBP Products)
    Background
    CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.
    UniProt
    P45481
    Pathways
    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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