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C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 45-209) protein (Fc Tag)

CLEC6A Origin: Mouse Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS
Catalog No. ABIN2745635
  • Target See all C-Type Lectin Domain Family 6, Member A (CLEC6A) Proteins
    C-Type Lectin Domain Family 6, Member A (CLEC6A)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 45-209
    Origin
    • 3
    • 2
    • 1
    • 1
    Mouse
    Source
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    Fc Tag
    Application
    SDS-PAGE (SDS)
    Cross-Reactivity
    Mouse (Murine)
    Characteristics
    Mouse dectin-2 (aa 45-209) is fused at the C-terminus to the Fc portion of human IgG1.
    Purity
    >95 % (SDS-PAGE)
    Endotoxin Level
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product CLEC6A Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 50 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Target
    C-Type Lectin Domain Family 6, Member A (CLEC6A)
    Alternative Name
    Dectin-2 (CLEC6A Products)
    Synonyms
    CLEC4N Protein, CLECSF10 Protein, CLEC6A Protein, C-type lectin domain containing 6A Protein, C-type lectin domain family 6, member A Protein, CLEC6A Protein, Clec6a Protein
    Background
    Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
    Molecular Weight
    ~58kDa (SDS-PAGE)
    UniProt
    Q9JKF4
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