DLK1 Protein (AA 24-303, Extracellular Domain) (Fc Tag)
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- Target See all DLK1 Proteins
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Extracellular Domain, AA 24-303
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DLK1 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Signal peptide and extracellular domain of human DLK1 (aa 24-303) are fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >90 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product DLK1 Protein
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delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-383) protein (rho-1D4 tag,MBP tag)
Crystallography grade DLK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-305) protein (His tag)DLK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) protein (His tag)DLK1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) protein (Fc Tag)DLK1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-306) protein (His tag)DLK1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 25-383) protein (GST tag)DLK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) protein (His tag)Crystallography grade DLK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-305) protein (His tag)Crystallography grade DLK1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) protein (rho-1D4 tag)Crystallography grade DLK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-385) protein (rho-1D4 tag)Crystallography grade DLK1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Inhibits adipogenesis of 3T3L-1 cells.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS + 0.02 % CHAPS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- Alternative Name
- DLK1 (DLK1 Products)
- Synonyms
- DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, Zog Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 homolog (Drosophila) Protein, delta-like 1 (Drosophila) Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, Dlk1 Protein
- Background
- The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
- Molecular Weight
- ~65kDa (SDS-PAGE)
- UniProt
- P80370
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