FNDC4 Protein (AA 41-163, Extracellular Domain)
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- Target See all FNDC4 Proteins
- FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular Domain, AA 41-163
- Origin
- Human, Mouse, Dog, Monkey, Rat
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Dog (Canine), Human, Monkey, Mouse (Murine), Rat (Rattus)
- Characteristics
- FNDC4 (extracellular domain, human (aa 45-167) / mouse (aa 41-163)) is untagged. FNDC4 extracellular domain has 100 % identity between human, mouse, rat, dog and monkey.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FNDC4 Protein
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Fibronectin Type III Domain Containing 4 (FNDC4) (AA 45-148) protein (His-IF2DI Tag)
FNDC4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 1-234) protein (GST tag)FNDC4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 45-154) protein (GST tag)FNDC4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 45-167) protein (His tag)Crystallography grade FNDC4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 41-163) protein (His tag)Crystallography grade FNDC4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 45-234) protein (rho-1D4 tag)Crystallography grade FNDC4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 41-231) protein (rho-1D4 tag)Crystallography grade FNDC4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fibronectin Type III Domain Containing 4 (FNDC4) protein (Myc-DYKDDDDK Tag)FNDC4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
- Alternative Name
- FNDC4 (FNDC4 Products)
- Synonyms
- 2810430J06Rik Protein, 6330410H20Rik Protein, AB030187 Protein, AI838506 Protein, AW487863 Protein, FRCP1 Protein, Fnmp1 Protein, FNDC4 Protein, fibronectin type III domain containing 4 Protein, Fndc4 Protein, FNDC4 Protein, fndc4 Protein
- Background
- Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50 % identity and 86 % similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
- Molecular Weight
- ~16kDa
- UniProt
- Q9H6D8
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