JAG2 Protein (AA 1-1054) (Fc Tag)
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- Target See all JAG2 Proteins
- JAG2 (Jagged 2 (JAG2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-1054
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This JAG2 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
- Purity
- >90 % (SDS-PAGE)
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
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Jagged 2 (JAG2) (AA 1102-1238) protein (His tag)Crystallography grade JAG2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Jagged 2 (JAG2) (AA 1104-1247) protein (His tag)Crystallography grade JAG2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Jagged 2 (JAG2) (AA 27-1080) protein (His tag)Crystallography grade JAG2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Jagged 2 (JAG2) (AA 24-1082) protein (His tag)Crystallography grade JAG2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Jagged 2 (JAG2) (AA 24-1238) protein (rho-1D4 tag)Crystallography grade JAG2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Jagged 2 (JAG2) (AA 24-1247) protein (rho-1D4 tag)Crystallography grade JAG2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS + 0.02 % CHAPS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- JAG2 (Jagged 2 (JAG2))
- Alternative Name
- Jagged-2 (JAG2 Products)
- Background
- Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
- Molecular Weight
- ~150kDa (SDS-PAGE)
- UniProt
- Q9Y219
- Pathways
- Notch Signaling, Sensory Perception of Sound
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