NMNAT1 Protein (AA 1-279) (His tag)
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- Target See all NMNAT1 Proteins
- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 1-279
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NMNAT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human full-length NMNAT1 (aa 1-279) is fused at the N-terminus to a His-tag.
- Purity
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product NMNAT1 Protein
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Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) (AA 1-279) protein (His tag)
NMNAT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) (AA 1-285) protein (His tag)NMNAT1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) (AA 1-279) protein (GST tag)NMNAT1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) (AA 51-150) protein (GST tag)NMNAT1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) protein (Myc-DYKDDDDK Tag)NMNAT1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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>5U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1μmol of NAD+ per min.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In 50 mM sodium phosphate, pH 8.0, containing 300 mM sodium chloride, 2 mM DTT and 10 % glycerol.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
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- Target
- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
- Alternative Name
- NMNAT1 (NMNAT1 Products)
- Synonyms
- id:ibd5068 Protein, im:7144541 Protein, zgc:110243 Protein, LCA9 Protein, NMNAT Protein, PNAT1 Protein, 2610529L11Rik Protein, 5730441G13Rik Protein, D4Cole1e Protein, nmnat Protein, nicotinamide mononucleotide adenylyltransferase 1 Protein, nicotinamide nucleotide adenylyltransferase 1 Protein, CpipJ_CPIJ015320 Protein, PTRG_06486 Protein, nmnat1 Protein, NMNAT1 Protein, Nmnat1 Protein
- Background
- Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
- Molecular Weight
- ~33.3kDa (monomer)
- UniProt
- Q9HAN9
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