PDCD1LG2 Protein (AA 20-219) (Fc Tag)
(1 reference)-
- Target See all PDCD1LG2 Proteins
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 20-219
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDCD1LG2 protein is labelled with Fc Tag.
- Sequence
- AA 20-219
- Characteristics
- This protein carreis a mouse IgG1 Fc tag at the C-terminus, and has a calculated MW of 48.9 kDa. The predicted N-terminus is Leu 20. The reducing (R) protein migrates as 60-70 kDa in SDS-PAGE due to glycosylation.
- Purity
- >95 % as determined by reduced SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PDCD1LG2 Protein
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Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (His-Avi Tag)
PDCD1LG2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His tag)PDCD1LG2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His-Avi Tag,Biotin)PDCD1LG2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (Fc Tag)PDCD1LG2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-121) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-220) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag)PDCD1LG2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) protein (His tag)PDCD1LG2 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag,AVI tag,Biotin)PDCD1LG2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (Fc Tag)PDCD1LG2 Origin: Cynomolgus Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).
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: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).
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- Target
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- Alternative Name
- PD-L2 (PDCD1LG2 Products)
- Synonyms
- PDL2 Protein, B7DC Protein, Btdc Protein, CD273 Protein, PD-L2 Protein, PDCD1L2 Protein, bA574F11.2 Protein, B7-DC Protein, F730015O22Rik Protein, programmed cell death 1 ligand 2 Protein, PDCD1LG2 Protein, Pdcd1lg2 Protein
- Background
- Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
- Molecular Weight
- 48.9 kDa
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