LMAN2 Protein (AA 45-322) (His tag)

Catalog No. ABIN4370706

Product Details

Target: LMAN2 (Lectin, Mannose-Binding 2 (LMAN2))

Protein Type: Recombinant

Protein Characteristics: AA 45-322

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This LMAN2 protein is labelled with His tag.

Purpose: Recombinant Human VIP36/LMAN2/GP36b (C-6His)

Sequence: DITDGNSEHL KREHSLIKPY QGVGSSSMPL WDFQGSTMLT SQYVRLTPDE RSKEGSIWNH QPCFLKDWEM HVHFKVHGTG KKNLHGDGIA LWYTRDRLVP GPVFGSKDNF HGLAIFLDTY PNDETTERVF PYISVMVNNG SLSYDHSKDG RWTELAGCTA DFRNRDHDTF LAVRYSRGRL TVMTDLEDKN EWKNCIDITG VRLPTGYYFG ASAGTGDLSD NHDIISMKLF QLMVEHTPDE ESIDWTKIEP SVNFLKSPKD NVDDPTGNFR SGPLTGWRVD HHHHHH

Characteristics: Recombinant Human Vesicular Integral-Membrane Protein VIP36/LMAN2 is produced by our mammalian expression system. The target protein is expressed with sequence (Asp45-Arg322) of Human LMAN2 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM TrisHCl,10 mM GSH, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: LMAN2 (Lectin, Mannose-Binding 2 (LMAN2))

Alternative Name: LMAN2 (LMAN2 Products)

Synonyms: Lman2 Protein, wu:fb16f04 Protein, zgc:158761 Protein, C5orf8 Protein, GP36B Protein, VIP36 Protein, 1110003H06Rik Protein, 1300009F09Rik Protein, AA408240 Protein, AL023023 Protein, AU040819 Protein, Vip36 Protein, lectin, mannose binding 2 Protein, lectin, mannose-binding 2 Protein, LMAN2 Protein, lman2 Protein, Lman2 Protein

Sub Type: Fusionprotein

Background: Vesicular integral-membrane protein VIP36 is also known as Glycoprotein GP36b, Lectin mannose-binding 2, Vesicular integral-membrane protein 36, LMAN2 and C5orf8. LMAN2 is widely expressed and contains one L-type lectin-like domain. LMAN2 binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. LMAN2 plays a role as an intracellular lectin in the early secretory pathway. LMAN2 interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. LMAN2 is also involved in the transport and sorting of glycoproteins carrying high mannose-type glycans.
Alternative Names: Vesicular Integral-Membrane Protein VIP36, Glycoprotein GP36b, Lectin Mannose-Binding 2, Vesicular Integral-Membrane Protein 36, VIP36, LMAN2, C5orf8

Molecular Weight: 32.7 kDa

UniProt: Q12907

Pathways: SARS-CoV-2 Protein Interactome