Vascular Endothelial Growth Factor 121 (Active) Protein

Details for Product No. ABIN4889934, Supplier: Log in to see
Protein Name
Origin
Human
5
1
Source
Escherichia coli (E. coli)
5
1
Protein Type
Recombinant
Biological Activity
Active
Application
ELISA, In vitro Assay (in vitro), In vivo Studies (in vivo), Western Blotting (WB)
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Sequence MPMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENCDKPR R
Purity ≥ 95%
Sterility 0.2 μm filtered
Endotoxin Level ≤ 1.00 LAL (EUs/ug)
Biological Activity Comment
  • Bioactivity Assay: HUVEC proliferation
  • Bioactivity Acceptance Criteria ED50 (ng/ml): 5 ng/mL
  • Bioactivity Acceptance Criteria (Units/mg): 2.0 x 10^5 units/mg
Protein Name
Background Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.

Alternate Names: VEGF-A, VPF, glioma-derived endothelial cell mitogen
Molecular Weight Dimer: 14.1/28.3 MW Monomer/Total (kDa)
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Media Components: Luria Broth

Restrictions For Research Use only
Format Lyophilized
Reconstitution Sterile water at 0.1 mg/mL
Buffer Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing : 0.1 % Trifluoroacetic Acid (TFA)
Preservative Without preservative
Handling Advice Centrifuge vial before opening.
Storage 4 °C,-20 °C,-80 °C
Storage Comment 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.
Expiry Date 12 months
Supplier Images
 image for Vascular Endothelial Growth Factor 121 (Active) protein (ABIN4889934) Vascular Endothelial Growth Factor 121 (Active) protein
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