WNT1 Inducible Signaling Pathway Protein 2 (WISP2) Protein

Details for Product No. ABIN4889942, Supplier: Log in to see
Protein Name
  • MGC84196
  • WISP2
  • ccn5
  • CCN5
  • CT58
  • CTGF-L
  • Ccn5
  • Crgr4
  • Ctgfl
  • Rcop1
  • WNT1 inducible signaling pathway protein 2
  • WNT1 inducible signaling pathway protein 2 S homeolog
  • WISP2
  • wisp2.S
  • wisp2
  • Wisp2
Origin
Human
14
3
1
Source
Escherichia coli (E. coli)
14
1
1
1
1
Protein Type
Recombinant
Application
ELISA, In vitro Assay (in vitro), In vivo Studies (in vivo), Western Blotting (WB)
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Sequence MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
Purity ≥ 95%
Sterility 0.2 μm filtered
Endotoxin Level ≤ 1.00 LAL (EUs/ug)
Biological Activity Comment
  • Bioactivity Assay: Currently undetermined
  • Bioactivity Acceptance Criteria ED50 (ng/ml): Currently undetermined
  • Bioactivity Acceptance Criteria (Units/mg): Currently undetermined
Protein Name
Background WNT1-inducible-signaling pathway protein 2 (WISP-2) is a member of the CYR61/CTGF/NOV (CCN) family of regulatory factors. WISP-2 is expressed in ectodermal, mesodermal, and endodermal lineages, including primary osteoblasts, fibroblasts, mesenchymal stem cells, and adipogenic precursor cells. WISP-2 is a canonical WNT ligand that regulates cell proliferation, adhesion, and metastasis. Secreted WISP-2 promotes mesenchymal precursor cell proliferation and maintains them in an undifferentiated state. In bone-forming osteoblasts, WISP-2 promotes osteoblast adhesion and inhibits osteocalcin production.

Alternate Names: CTGFL, Connective Tissue Growth Factor-Like protein, CCN5, CT-58
Molecular Weight Monomer: 24.4 MW Monomer/Total (kDa)
UniProt O76076
Pathways Growth Factor Binding
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Media Components: Luria Broth

Restrictions For Research Use only
Format Lyophilized
Reconstitution Sterile 10 mM acetic acid at 0.1 mg/mL
Buffer Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing : 0.1 % Trifluoroacetic Acid (TFA)
Preservative Without preservative
Handling Advice Centrifuge vial before opening.
Storage 4 °C,-20 °C,-80 °C
Storage Comment 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.
Expiry Date 12 months
Did you look for something else?