Fibroblast Growth Factor 6 (FGF6) (Active) Protein

Details for Product No. ABIN4889957, Supplier: Log in to see
Protein Name
  • FGF6
  • hst2
  • fgf-6
  • hbgf-6
  • HBGF-6
  • HST2
  • Fgf-6
  • HSTF-2
  • fgf4
  • fgf6
  • fibroblast growth factor 6
  • fibroblast growth factor 6a
  • FGF6
  • fgf6
  • Fgf6
  • fgf6a
Origin
Human
18
3
1
1
Source
Escherichia coli (E. coli)
23
Protein Type
Recombinant
Biological Activity
Active
Application
ELISA, In vitro Assay (in vitro), In vivo Studies (in vivo), Western Blotting (WB)
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Sequence MGTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI
Purity ≥ 95%
Sterility 0.2 μm filtered
Endotoxin Level ≤ 1.00 LAL (EUs/ug)
Biological Activity Comment
  • Bioactivity Assay: NR6R-3T3 Proliferation w 1 ug heparin
  • Bioactivity Acceptance Criteria ED50 (ng/ml): 1 ng/mL
  • Bioactivity Acceptance Criteria (Units/mg): 1.0 x 10^6 units/mg
Protein Name
Background Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.

Alternate Names: Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6
Molecular Weight Monomer: 18.9 MW Monomer/Total (kDa)
UniProt P10767
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Media Components: Luria Broth

Restrictions For Research Use only
Format Lyophilized
Reconstitution Sterile water at 0.1 mg/mL

If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10 % overfill has been added to compensate for any loss of protein in the precipitate.
Buffer Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing : 10 mM sodium phosphate and 50 mM sodium chloride,  pH 7.5
Preservative Without preservative
Handling Advice Centrifuge vial before opening.
Storage 4 °C,-20 °C,-80 °C
Storage Comment 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.
Expiry Date 12 months
Supplier Images
 image for Fibroblast Growth Factor 6 (FGF6) (Active) protein (ABIN4889957) Fibroblast Growth Factor 6 (FGF6) (Active) protein
Did you look for something else?