BCMA Protein (AA 1-54) (His tag)
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- Target See all BCMA (TNFRSF17) Proteins
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 1-54
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BCMA protein is labelled with His tag.
- Application
- Functional Studies (Func)
- Sequence
- AA 1-54
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.5 kDa. the protein migrates as 7-15 kDa under reducing (R) condition, and 15-18 kDa under non-reducing (NR) condition (SDS-PAGE).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFRSF17 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
- Alternative Name
- BCMA (TNFRSF17 Products)
- Background
- Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
- Molecular Weight
- 7.8 kDa
- NCBI Accession
- NP_001183
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