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FKBP4 Protein (AA 1-459) (His tag,PA tag)

FKBP4 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Func
Catalog No. ABIN4949097
  • Target See all FKBP4 Proteins
    FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-459
    Origin
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 4
    • 4
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This FKBP4 protein is labelled with His tag,PA tag.
    Application
    Functional Studies (Func)
    Sequence
    AA 1-459
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus, followed by a PA tag, and has a calculated MW of 55.1 kDa. The predicted N-terminus is Met 1. The reducing (R) protein migrates as 60 kDa in SDS-PAGE.
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product FKBP4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
    Alternative Name
    FKBP4 (FKBP4 Products)
    Synonyms
    HBI Protein, p52 Protein, hsp56 Protein, PPIase Protein, fkbp52 Protein, fkbp59 Protein, MGC81078 Protein, wu:fb34f09 Protein, 59kDa Protein, AL022792 Protein, AW208983 Protein, FKBP-4 Protein, FKBP-52 Protein, FKBP52 Protein, FKPB52 Protein, p59 Protein, FKBP51 Protein, FKBP59 Protein, Hsp56 Protein, P59 Protein, FK506 binding protein 4 Protein, FK506 binding protein 4 S homeolog Protein, FKBP4 Protein, fkbp4.S Protein, fkbp4 Protein, Fkbp4 Protein
    Background
    Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.
    Molecular Weight
    55.1 kDa
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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