QPCT Protein (AA 29-361) (His-SUMO Tag)
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- Target See all QPCT Proteins
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-361
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This QPCT protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR SFSNIISTLN PTAKRHLVLA CHYDSKYFSH WNNRVFVGAT DSAVPCAMML ELARALDKKL LSLKTVSDSK PDLSLQLIFF DGEEAFLHWS PQDSLYGSRH LAAKMASTPH PPGARGTSQL HGMDLLVLLD LIGAPNPTFP NFFPNSARWF ERLQAIEHEL HELGLLKDHS LEGRYFQNYS YGGVIQDDHI PFLRRGVPVL HLIPSPFPEV WHTMDDNEEN LDESTIDNLN KILQVFVLEY LHL
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product QPCT Protein
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Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 1-361) protein (GST tag)
QPCT Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 262-359) protein (GST tag)QPCT Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 36-362) protein (His tag)Crystallography grade QPCT Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 29-361) protein (His-SUMO Tag)QPCT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Glutaminyl-Peptide Cyclotransferase (QPCT) protein (Myc-DYKDDDDK Tag)QPCT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
- Alternative Name
- QPCT (QPCT Products)
- Synonyms
- GCT Protein, QC Protein, sQC Protein, QPCT Protein, 5730422A13Rik Protein, Qpctl1 Protein, RGD1562284 Protein, qpct Protein, glutaminyl-peptide cyclotransferase Protein, glutaminyl-peptide cyclotransferase (glutaminyl cyclase) Protein, glutaminyl-peptide cyclotransferase L homeolog Protein, QPCT Protein, Qpct Protein, M6_Spy0443 Protein, M5005_Spy_0416 Protein, M28_Spy0404 Protein, CJA_2408 Protein, CCNA_02733 Protein, Tsp_03182 Protein, qpct.L Protein
- Background
- Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.
- Molecular Weight
- 53.9 kDa
- UniProt
- Q16769
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