C10orf2 Protein (AA 32-684) (His tag)
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- Target See all C10orf2 (C10ORF2) Proteins
- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-684
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This C10orf2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- APGPPRRRYR KETLQALDMP VLPVTATEIR QYLRGHGIPF QDGHSCLRAL SPFAESSQLK GQTGVTTSFS LFIDKTTGHF LCMTSLAEGS WEDFQASVEG RGDGAREGFL LSKAPEFEDS EEVRRIWNRA IPLWELPDQE EVQLADTMFG LTKVTDDTLK RFSVRYLRPA RSLVFPWFSP GGSGLRGLKL LEAKCQGDGV SYEETTIPRP SAYHNLFGLP LISRRDAEVV LTSRELDSLA LNQSTGLPTL TLPRGTTCLP PALLPYLEQF RRIVFWLGDD LRSWEAAKLF ARKLNPKRCF LVRPGDQQPR PLEALNGGFN LSRILRTALP AWHKSIVSFR QLREEVLGEL SNVEQAAGLR WSRFPDLNRI LKGHRKGELT VFTGPTGSGK TTFISEYALD LCSQGVNTLW GSFEISNVRL ARVMLTQFAE GRLEDQLDKY DHWADRFEDL PLYFMTFHGQ QSIRTVIDTM QHAVYVYDIC HVIIDNLQFM MGHEQLSTDR IAAQDYIIGV FRKFATDNNC HVTLVIHPRK EDDDKELQTA SIFGSAKASQ EADNVLILQD RKLVTGPGKR YLQVSKNRFD GDVGVFPLEF NKNSLTFSIP PKNKARLKKI KDDTGPVAKK PSSGKKGATT QNSEICSGQA PTPDQPDTSK RSK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product C10ORF2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
- Alternative Name
- PEO1 (C10ORF2 Products)
- Synonyms
- ATXN8 Protein, IOSCA Protein, MTDPS7 Protein, PEO Protein, PEO1 Protein, PEOA3 Protein, SANDO Protein, SCA8 Protein, TWINL Protein, C6H10orf2 Protein, D19Ertd626e Protein, Twinl Protein, twinkle mtDNA helicase L homeolog Protein, twinkle mtDNA helicase Protein, twnk.L Protein, TWNK Protein, Twnk Protein
- Background
- Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as tplate to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals.
- Molecular Weight
- 75.45 kDa
- UniProt
- Q96RR1
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