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PTPRN Protein (DYKDDDDK Tag)

PTPRN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN5505753
  • Target See all PTPRN Proteins
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    Protein Type
    Recombinant
    Origin
    • 11
    • 3
    • 1
    Human
    Source
    • 8
    • 6
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PTPRN protein is labelled with DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PTPRN (full length, C-term DDK tag, transcript variant 1) protein expressed in Human HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PTPRN Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    Alternative Name
    PTPRN (PTPRN Products)
    Synonyms
    IA-2 Protein, IA-2/PTP Protein, IA2 Protein, ICA512 Protein, R-PTP-N Protein, mIA-A Protein, mKIAA4064 Protein, Ia-2 Protein, fc43c04 Protein, ptprn Protein, wu:fc43c04 Protein, ia-2 Protein, ia2 Protein, ica512 Protein, r-ptp-n Protein, protein tyrosine phosphatase, receptor type N Protein, protein tyrosine phosphatase, receptor type, N Protein, protein tyrosine phosphatase, receptor type, Na Protein, protein tyrosine phosphatase, receptor type N L homeolog Protein, PTPRN Protein, Ptprn Protein, ptprna Protein, ptprn.L Protein
    Background
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010].
    Molecular Weight
    103 kDa
    NCBI Accession
    NP_002837
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