NMNAT2 Protein (AA 2-307) (His tag)
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- Target See all NMNAT2 Proteins
- NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-307
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NMNAT2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human NMNA2 (aa 2-307) is fused at the N-terminus to a His-tag.
- Purity
- >90 % (SDS-PAGE)
- Top Product
- Discover our top product NMNAT2 Protein
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Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (His tag)
NMNAT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-302) protein (GST tag)NMNAT2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (GST tag)NMNAT2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 208-307) protein (GST tag)NMNAT2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (Strep Tag)Crystallography grade NMNAT2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (Strep Tag)Crystallography grade NMNAT2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NMNAT2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Concentration
- Lot specific
- Buffer
- Lyophilized in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl plus 0.025 % CHAPS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
- Alternative Name
- NMNAT2 (NMNAT2 Products)
- Synonyms
- zgc:73048 Protein, wu:fj59g01 Protein, NMNAT2 Protein, C1orf15 Protein, PNAT2 Protein, AI843915 Protein, D030041I09Rik Protein, PNAT1 Protein, nicotinamide nucleotide adenylyltransferase 2 Protein, nmnat2 Protein, NMNAT2 Protein, Nmnat2 Protein
- Background
- Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration (axon degeneration induced by nerve injury), whereas NMNAT overexpression rescues axons from degeneration.
- Molecular Weight
- ~35kDa (SDS-PAGE)
- UniProt
- Q9BZQ4
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