TNFSF9 Protein (AA 104-309, Extracellular Domain, Soluble) (DYKDDDDK Tag)
-
- Target See all TNFSF9 Proteins
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 104-309, Extracellular Domain, Soluble
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFSF9 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds to mouse CD137.
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- The extracellular domain of mouse CD137L (aa 104-309) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFSF9 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Solid
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 6 months
-
- Target
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- Alternative Name
- CD137L (TNFSF9 Products)
- Synonyms
- TNFSF9 Protein, 4-1BB-L Protein, 4-1BBL Protein, AI848817 Protein, Cd137l Protein, Ly63l Protein, CD137L Protein, TNF superfamily member 9 Protein, tumor necrosis factor (ligand) superfamily, member 9 Protein, Tnfsf9 Protein, LOC476729 Protein, TNFSF9 Protein
- Background
- The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
- Molecular Weight
- ~40kDa (SDS-PAGE)
- UniProt
- P41274
- Pathways
- Activated T Cell Proliferation, Cancer Immune Checkpoints
-