TNFSF9 Protein (AA 85-254, Soluble) (Fc Tag)
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- Target See all TNFSF9 Proteins
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 85-254, Soluble
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFSF9 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds to human CD137 receptor.
- Cross-Reactivity
- Human
- Characteristics
- The receptor-binding domain of human CD137L (aa 85-254) is fused at the N-terminus to the Fc portion of human IgG1.
- Purity
- >90 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFSF9 Protein
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Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Trimer) protein (Fc Tag)
TNFSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Trimer) protein (His tag)TNFSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 68-251) protein (Fc Tag)TNFSF9 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Trimer) protein (Fc Tag,Biotin)TNFSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) protein (mFc-His Tag)TNFSF9 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 50-254) protein (His-DYKDDDDK-Strep II Tag)TNFSF9 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Active) protein (His tag,AVI tag)TNFSF9 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Active) protein (His tag)TNFSF9 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 71-254) protein (His tag)TNFSF9 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 145-254) protein (GST tag)TNFSF9 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- Alternative Name
- CD137L (TNFSF9 Products)
- Synonyms
- TNFSF9 Protein, 4-1BB-L Protein, 4-1BBL Protein, AI848817 Protein, Cd137l Protein, Ly63l Protein, CD137L Protein, TNF superfamily member 9 Protein, tumor necrosis factor (ligand) superfamily, member 9 Protein, Tnfsf9 Protein, LOC476729 Protein, TNFSF9 Protein
- Background
- The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes and in T and B cell co-stimulation and modulation of the immune response.
- Molecular Weight
- ~46kDa (SDS-PAGE)
- UniProt
- P41273
- Pathways
- Activated T Cell Proliferation, Cancer Immune Checkpoints
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